What Are The Side Effects Of Melatonin
“While many studies have examined melatonin, the side effects aren’t firmly established,” says Dr. Ramkissoon.
The most commonly reported melatonin side effects include:
- Daytime sleepiness
“Certain studies also report short-term feelings of depression and irritability, as well as stomach cramps,” adds Dr. Ramkissoon.
Lastly, since supplements aren’t regulated by the FDA like over-the-counter and prescription medications are, you’ll need to do some research to be sure you’re getting a quality product that has undergone testing and been certified by an independent third-party laboratory, such as NSF.
For instance, a 2017 study testing more than 30 different melatonin supplements found that the amount of melatonin in the product often didn’t match what was listed on the label, and that some products contained ingredients other than melatonin. These are issues that can affect the side effects a person experiences, as well as the product’s overall safety.
Can I Take Melatonin With Caffeine
Caffeine is a stimulant, and billions of people consume it daily. Since it stimulates the central nervous system, it is likely to promote feelings of alertness in users.
Caffeine intake tends to lower the bodys melatonin production and thus can cause a disruption to your normal sleep-wake cycle. According to Sleep Foundation, this stimulant can delay sleep onset if a person consumes it before bedtime.
The combination might not be dangerous or fatal but could cause you to be increasingly alert. Note that melatonin is not a sedative. Thus, it may not have an antagonizing effect on caffeine as one might suppose.
However, depending on the dosage of caffeine consumed, the combination is most likely going to increase your alertness and annul the effects of the melatonin.
What Not To Take With Melatonin
Because melatonin can affect your sleep-wake cycle, avoid taking it with alcohol or caffeine. These can interfere with your circadian rhythm and your natural melatonin production.
Before starting melatonin or any over-the-counter medication or supplement, talk with your doctor. This is especially true if you take other medications.
For example, birth control pills may cause your body to start producing more melatonin, so taking a supplement could push your levels into an unhealthy range.
Taking melatonin with anticoagulant drugs, such as warfarin , could increase your risk of bleeding.
You should also avoid taking melatonin if you take corticosteroids to suppress your immune response for conditions such as rheumatoid arthritis or lupus.
If you think you may have overdosed on melatonin, call Poison Control at 800-222-1222.
You should call 911 and seek emergency help if you have symptoms such as:
- shortness of breath
- sudden chest pain
- blood pressure thats 180/120 mm Hg or higher
These signs may not be related to melatonin or an interaction between melatonin and other medications. However, they shouldnt be ignored, as they can indicate a medical emergency.
Though melatonin can be very helpful for some people needing a little extra help falling and staying asleep, its not for everyone. You may not tolerate it well, even at low doses. You may find that it doesnt help you sleep, regardless of the dose you try.
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How Much Melatonin Is Too Much
Taken on a short-term basis, melatonin has very few side effects and when they do appear, they tend to be mild. Research shows that some side effects of taking melatonin can include headache, dizziness, nausea, and sleepiness.3Low dose melatonin can safely be taken for up to 3 months, however doses higher than 5 mg should not be taken for longer than 2 months.
If youre pregnant or nursing, you should consult your physician before taking melatonin. Keep in mind that, like all supplements, melatonin might interact with certain medications, such as antidepressants, blood pressure or blood thinning medicines so best to check with your doctor or pharmacist before taking melatonin if you are taking prescription medications. In older adults, melatonin may remain active in their bodies longer than it does in younger people and also may cause daytime lethargy.3
Learn More: Is It Safe to Take Melatonin While Pregnant?
The Bottom Line
If you struggle to fall asleep once your head hits the pillow, you might benefit from taking melatonin to help regulate your bodys sleep cycle. The optimal melatonin dose depends on your age, so start with the lowest dose of melatonin as may be effective to meet your needs. If youre not sure whether takinga melatonin supplement is the right choice for you , talk with your health care professional for guidance and support.
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References
Melatonin Dosage For Adults

- Melatonin for Trouble Falling Asleep0.3 to 5 mg of melatonin, not to exceed nine months, may help people who have trouble falling asleep6
- Melatonin for Disrupted Sleep-Wake Cycle2 mg to 12 mg taken at bedtime for up to four weeks may help get your natural rhythm back on track6
- Melatonin for Extended Difficulty SleepingMost research studies have used 2 mg to 3 mg of controlled-release melatonin for up to 29 weeks. Doses of up to 12 mg daily have also been studied for shorter durations 6
- Melatonin for Blood Pressure Support2 mg to 3 mg of a controlled-release melatonin for up to four weeks6
- Melatonin for Jet Lag0.5 mg to 8 mg at bedtime is commonly taken starting the night of arrival at your destination, continuing for two to five days6
The above intake amounts have been studied scientifically, but always check with your doctor first before supplementing your melatonin to find the safest intake for your individual needs.6
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How Long Does Melatoninlast For Sleep
Disclaimer: This article is for informational purposes only and should not be taken as medical advice.
Weve all had restless nights. Whether tossing and turning is a nightly occurrence or this is the first time youre up counting sheep, youve likely heard of the popular sleep aid melatonin. But what is melatonin, and how long does melatonin last for sleep?
Melatonin is a naturally occurring hormone that can help promote sleepiness, so you fall asleep fast. Many people have turned to melatonin supplements, which are available over the counter, to help them catch some zzzs in a pinch.
Before using melatonin, its essential to understand the potential impacts it can have on your health. Keep reading to learn everything you need to know about using melatonin for sleep.
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Who Should Take Melatonin And Who Shouldnt
If youre interested in taking melatonin, or if you think you might have a sleep disorder, you should see your healthcare provider who can help diagnose and treat the problem.
If you take too much melatonin, or take it too late in the evening, you can cause yourself to be drowsy, sluggish or have delayed reaction times during the day when you should be more alert. Some common side effects of taking melatonin can include:
- Abdominal cramps.
- Temporary feelings of depression.
Its also important to note that some sleep disorders, like insomnia, can gradually worsen when you take melatonin, especially if youre taking higher doses .
A person who has trouble falling asleep or staying asleep no matter what time it is wont benefit much from melatonin, says Dr. Roth.
Melatonin works differently for everyone, and doctor recommendations vary based on your diagnosis and sleep history. With chronic conditions like insomnia or other similar sleep disorders, its best to see a sleep specialist to get a correct diagnosis and consider cognitive behavioral therapy or other treatments.
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Melatonin Gummies: Dosage For Breastfeeding & Pregnant Women
Breastfeeding women, pregnant women, or women trying to get pregnant must take utmost care before using any drugs or supplements. Several medical associations consider melatonin supplementation to be generally safe. However, since there are still many unknowns about its overall effects, it might be best to stay off if youre pregnant or breastfeeding.
During the entire pregnancy, the placenta produces melatonin all day. However, pregnant women diagnosed with preeclampsia often have low melatonin levels. In this case, melatonin supplementation might help if a doctor recommends it.
Several animal studies have been carried out to research how melatonin supplementation affects pregnant women. The studies show that melatonin supplementation may not be completely safe during pregnancy.
However, several other studies showed that taking melatonin supplements such as gummies while pregnant is probably safe. Although there is a shortage of randomized controlled trials to this effect, there are a handful of clinical trials and cohort studies that prove this. In most of these studies, there were no major safety concerns for melatonin supplementation in pregnant women.
The perinatal period for several women is often fraught with many sleep issues. For this reason, many pregnant women seek natural sleep aids at some point during their pregnancy. This has caused widespread curiosity about the safety of using melatonin gummies and other sleep aids during pregnancy/lactation.
What Is The Usual Prognosis For A Melatonin Overdose
Melatonin is generally safe for most people, and many people wont experience major complications when taking too much. Even so, an overdose can cause unpleasant side effects.
Keep your dose to no more than 1 to 3 mg per night. See your doctor for any serious side effects or if sleep problems dont improve after a few weeks. You may need to consult a sleep specialist.
A sleep specialist can help diagnose a sleep disorder, as well as make other suggestions to help you get a better nights sleep.
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Alternatives To Taking Melatonin
If you have trouble sleeping, it is always wise to see a doctor. A doctor can assess your symptoms and determine if a medical condition may be an underlying cause. If that turns out to be the case, your doctor can then identify treatment options that may also allow you to sleep soundly.
If you want a more restful sleep without melatonin supplements, start by establishing a sleep/wake routine. By following the same schedule nightly, you can create a pattern that your body gets used to, increasing the odds that youll be sleepy at the right time.
Avoid caffeine, alcohol, exercise and digital devices at least a few hours before bed. All of those things can disrupt your natural melatonin production, so forgoing them as the evening approaches can help. Anxiety can also hamper sleep. Finding natural ways to relieve stress can help.
For some, herbal tea can promote better sleep. Some find consuming them relaxing, and that general sense of calm can make a difference.
Finding The Right Melatonin Dose With Omega Restore
Working with customers has made me formulate this general guideline to finding your optimal Omega Restore dose:
Start with the lowest dose and work your way up as necessary. We typically recommend starting with a 2 mg dose and increasing from there as needed.
If you do not feel any difference in your sleep pattern after 5 to 7 days, increase the dose.
If you get too high a dose meaning, you experience frequent or early waking then reduce the dose. You can always reduce the dose by taking half a vial .
When you find the best dose for you, you should wake up feeling refreshed in the morning, as well as feel less stressed and tired during the day. When you have found this personal best dose, there doesnt seem to be much change over time.
Personally, I increase my nightly dose while traveling internationally. This seems to take away any jet lag issues. If I feel after some time that Omega Restore seems to work less, then I skip taking the vial for a few days for the body to break down any surplus.
If you have questions about using Omega Restore or finding your right dose, give us a call at 866.414.0188 or leave a comment below.
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Whats The Most Popular Dose
Most individuals will do fine on a two to two-and-a-half milligram dose, says Dr. Chelsie Rohrscheib, Ph.D., neuroscientist and Head Sleep Specialist at Wesper. Using more than five milligrams of melatonin per night isnt recommended unless youre working closely with your doctor. Typically, 10 milligram options arent available over the counter and would only be recommended for those who suffer from blindness and non-24 hour sleep-wake disorder, explains Dr. Durmer. Too much melatonin can actually disrupt the circadian rhythm and make sleep more difficult, Dr. Rohrscheib adds. When you first start low and go slow, Dr. Rohrscheib recommends beginning with a half or one milligram one hour before bedtime, then increasing in small increments until you find a dose that works for you.
Is Melatonin Safe To Take Every Night

Americans arent sleeping well. Roughly 80% of U.S. adults say they struggle to fall asleep at least one night a week, according to a recent Consumer Reports survey. And research has found that sleep problems are also on the rise among adolescents.
While the causes of Americas sleep woes are up for debate, theres little disagreement about Americas favorite remedy: Melatonin, the countrys most-used sleep aid.
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What’s The Recommended Dose Of Melatonin
There is no official guideline for melatonin dosage. In general, experts suggest you start at the lowest available amount and gradually increase it until you get restful sleep.
Some experts calculate melatonin dosage by weight. For every kilogram you weigh, you can take 0.04 mg to 0.08 mg of melatonin a day. So, for example:
- An adult who weighs 155 pounds can take 3 mg to 6 mg of melatonin.
- A 6-year-old child who weighs 41 pounds can take 0.75 mg to 1.5 mg of melatonin.
Another way to calculate dosage that you may find more practical is to follow the recommended ranges for each age group:
- Children: 0.5 mg to 5 mg
- Adults: 0.5 mg to 10 mg
- Older adults: 0.1 mg to 5 mg
Note that these ranges are for short-term use only. Depending on the supplement you’re taking, “short-term” could mean anywhere from 5 days to 13 weeks. There is little research on what doses are safe to use long-term, so you may want to avoid taking supplements past the period recommended by your healthcare provider.
When To Take Melatonin
Everyone reacts differently, but in most cases, youll want to take melatonin about 30 minutes before bed because it takes about 20 to 40 minutes to work.
Its not a sedative, so its not going to knock you out, notes Dr. Roth. Melatonin is like a little dose of nighttime. It tells that melatonin system to turn on.
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What Does Melatonin Do
Research has shown that taking melatonin supplements is especially helpful for people who have specific sleep problems. Its useful in resetting your body from jet lag. It can help people who have trouble falling asleep if they are anxious about something like surgery.
Melatonin can help make children feel sleepier before bedtime. This helps them wind down and go to sleep earlier than they would without the supplement.
Melatonin is especially helpful in helping kids with specific health or behavior conditions, including:
Children who have these issues tend to have trouble falling asleep on their own. Melatonin supplements help them get to sleep more easily.
Can I Take Melatonin Every Night
Melatonin is generally safe for short-term use, but further research is required to assess the long-term safety of melatonin use. In the United States, melatonin is considered a dietary supplement, which are regulated less strictly by the Food and Drug Administration than prescriptions and over-the-counter medications. Federal law doesnt require dietary supplements to be proven safe to FDAs standards before they are sold.
Furthermore, some melatonin supplements may not contain what is listed on the product label. Researchers tested 31 commercial supplements and found that most products contained far more or far less melatonin than what was listed on the label. Some supplements contained serotonin, a hormone that wasnt recognized on the product label.
Although melatonin is generally regarded as well-tolerated, it may not be ideal for long-term use, unless specifically instructed by your doctor. Supplemental melatonin shifts the phase of the human circadian clock, and thus warrants caution. The principle of treatment of sleep disorders is first to find the cause of the sleep disturbance, and then treat the conditions causing the distress.
Treatment options for primary sleep disorders, or sleep disorders that arent caused by another medical or psychological condition, often include behavioral therapies. Sleep hygiene, sleep restriction, stimulus control, relaxation training, and cognitive therapy are examples of such therapies.
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Comparison Table: The Correct Dosage Melatonin 300mcg
See below to see an easy-to-read comparison table of the few companies online that sell melatonin 300mcg. Its shocking to see how many companies sell melatonin 1mg, 3mg, 5mg, and 10mgand how few sell melatonin 0.3mg.
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MedicalGeeker Rating 8.0/10 |
How Much Melatonin Can A Person Take
There is no official melatonin dose recommendation for adults, however a range of 0.5 milligrams to 5 milligrams appears to be safe and beneficial. Melatonin can be taken by adults one hour before going to bed. The best results appear to be when it is taken at least three hours apart from other medications that cause sleepiness, such as caffeine or alcohol.
The safety of melatonin for children has not been established. Children may be more sensitive to the effects of medication so it is recommended that small doses be used initially with gradual increases in dosage until the desired effect is achieved. The recommended starting dose is 1/8 of an adult dose given at night time. A maximum daily dose of 10 mg is advised.
Melatonin does not cure any disease or condition, prevent any disease or condition, or improve any quality of life. It is not intended to treat or diagnose any medical condition. It may help people get better sleep but it can’t make you sleep more or less than what you naturally would if you weren’t struggling with insomnia. If you think you may have a problem sleeping and are considering using melatonin, talk to your doctor first.
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