What May Interact With This Medication
- Medications for diabetes
- Steroid medications like prednisone or cortisone
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Dosage For Primary Hypogonadism
Adult dosage
- Typical starting dosage: Your dosage depends on your age and diagnosis. Your doctor will decide a dosage based on your needs. In general, the dosage is 50400 mg injected into your muscle every 24 weeks.
- Dosage increases: Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects.
- Maximum dosage: 400 mg injected into your muscle every 2 weeks.
Child dosage
- Typical starting dosage: Your childs dosage depends on their age and diagnosis. Your doctor will decide a dosage based on your childs needs. In general, the dosage is 50400 mg injected into your childs muscle every 24 weeks.
- Dosage increases: Your doctor may adjust your childs dosage based on their testosterone blood levels, response to treatment, and side effects.
- Maximum dosage: 400 mg injected into your childs muscle every 2 weeks.
Child dosage
It hasnt been confirmed that testosterone cypionate is safe and effective for use in children younger than 12 years.
Effects On Lactation And Breastmilk
Supraphysiologic serum levels of testosterone, either from a tumor or from exogenously administered testosterone, reduces milk production in postpartum women. Testosterone alone reduces serum prolactin however, when given in combination with estrogen and progestin, serum prolactin levels are not markedly reduced. Testosterone was previously used therapeutically to suppress lactation, usually in combination with an estrogen.
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What Happens When You Start Taking Testosterone
Hormonal changes
Normal testosterone metabolism results in the formation of two primary metabolites, namely, DHT and estradiol .
Elevated levels of DHT can cause:
- Benign growth of the prostate
- Increased oiliness of the skin and acne
- Male pattern balding
- Low testosterone levels, erectile dysfunction, and a decrease in free testosterone
Prostate changes
People with a first-degree relative diagnosed with prostate cancer, as well as those with an elevated prostate-specific antigen level, should proceed with caution and be closely monitored.
Treatment should not be considered for men who have a personal history of prostate cancer. TRT does not cause prostate cancer, but it is possible that elevated testosterone levels can cause an otherwise undetected prostate cancer lesion to grow more aggressively.
Fertility problems
When testosterone levels are restored, either naturally or through treatment, the brain reduces the stimulus to produce testosterone by secreting less gonadotropin-releasing hormone . Because this single hormone regulates both follicle-stimulating hormone and luteinizing hormone, the natural suppression of GnRH can reduce fertility. Furthermore, this process is responsible for the shrinkage and change in firmness in the testicles.
Erythrocytosis
According to studies, TRT causes increased RBC count that can make the blood more viscous. Hematocrit levels higher than 54.0% increase a persons risk of:
- Abnormal clotting
What If I Decide To Discontinue Testosterone Treatment

If you wish to discontinue testosterone therapy, we will help you do it safely. It is important to avoid abrupt discontinuation. In such cases, it may take time for your body to begin producing adequate testosterone again, and withdrawal reactions may occur. To prevent withdrawal reactions, your doctor may reduce your dose gradually and use other medications to stimulate your natural production. Consult your doctor for more details, and report any withdrawal reactions immediately.
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Treating Low Testosterone Levels In Males
Doctors may recommend testosterone injections to treat males with low testosterone levels. Low testosterone production by the testicles is called hypogonadism.
Low testosterone can have negative effects. The symptoms of low testosterone in males include a lower sperm count, a decrease in bone or muscle mass, increased body fat, and erectile dysfunction. Normal total testosterone levels in the bloodstream in healthy adult males are 2801,100 nanograms per deciliter .
When treating hypogonadism, testosterone therapy can have the
- increased lean muscle mass and strength
Effect Of Testosterone: Your Mood Can Improve
Similar to its effects on energy, experts don’t have a definitive answer to why testosterone impacts mood so deeplyafter all, “the brain is a complicated thing,” says Dr. Tamlerbut they do see it as a potential life-changing benefit.
“In some ways, the impact on mood is one of the most profound benefits of T that we see,” says Dr. Morgentaler. “Not everybody has that, but when we see it, it’s remarkable. In my practice, patients will say, ‘Oh, my mood’s OK, maybe I just feel a little bit tired or blah.’ And they come back and they say things like, ‘I wake up in the morning and I’m optimistic about my day. I haven’t felt that way in years.'”
In fact, a 2012 study published in The Aging Male found that after 12 months of testosterone therapy, the percentages of guys with moderately severe to severe depression symptoms decreased from 17 percent to 2 percent.
And more recent research also backs that up: “The largest randomized control trial for T was just completed a year ago, called the T Trials, and it showed that men who received T had a greater improvement in mood than men who received placebo,” notes Dr. Morgentaler.
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Uses Of Testosterone Cypionate Injection
The primary use of testosterone cypionate injections is for helping restore testosterone levels to a healthy range. Thus, testosterone cypionate is especially useful for treating low T in men.
Low T is a condition in which the body has inadequate endogenous production of testosterone.
Since testosterone is a vital hormone for overall health and wellness, males with low T often experience a myriad of debilitating symptoms when their testosterone levels drop below the desired range. These symptoms may include:
- Lack of sex drive
- Inability to concentrate
- Erectile dysfunction
- Infertility Increase in body fat Loss of body and pubic hair General fatigue
- Low red blood cell count
- Feeling like you cant get enough sleep Development of breast tissue
The good news is that the vast majority of men who use testosterone cypionate for TRT notice that these symptoms resolve within a matter of months . Testosterone is arguably the most vital hormone for a mans vitality, especially as you grow older.
As such, its crucial that you keep an eye on your testosterone levels, particularly if youre experiencing the symptoms of low T and/or youre 30+ years of age. Contact Gameday Mens Health today and a licensed physician can order the proper assays for you, as well as educate you more about TRT and help you decide if youre a good candidate for using testosterone cypionate injections.
Warnings For Other Groups
For pregnant women: Testosterone cypionate is a category X pregnancy drug. Category X drugs should never be used during pregnancy.
This drug should only be used in males.
For seniors: This drug shouldnt be used to treat age-related decreases in testosterone. There isnt enough information from clinical trials in seniors ages 65 years and older to support the use of this drug for a long period of time.
If youre older than 65 years, you may be at a higher risk of heart disease, prostate cancer, and enlarged prostate while taking this drug.
For children: It hasnt been confirmed that testosterone cypionate is safe and effective for use in children younger than 12 years.
Testosterone cypionate may affect bone growth in children. This drug can cause bones to mature more quickly than normal without causing an increase in height. This can result in a shorter adult height. Your doctor will check your childs growth regularly if your child takes this drug.
All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:
- how severe your condition is
- other medical conditions you have
- how you react to the first dose
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Increased Risk Of Prostate Cancer
While more studies are needed in this regard, there is some concern that testosterone products may increase the risk of developing prostate cancer.
One 2015 of existing observational studies concluded that the evidence was not strong enough but that larger studies in the future may find different results. A doctor should conduct a prostate cancer screening before prescribing testosterone medications.
What Is Testosterone Injection
Testosterone is a naturally occurring sex hormone produced in a man’s testicles. Small amounts of testosterone are also produced in a woman’s ovaries and adrenal system.
Testosterone injection is used in men and boys to treat conditions caused by a lack of this hormone, such as delayed puberty, impotence, or other hormonal imbalances. Testosterone injection is not for use in treating low testosterone without certain medical conditions or due to getting older.
Testosterone enanthate is used in women to treat breast cancer that has spread to other parts of the body and cannot be treated with surgery.
Testosterone will not enhance athletic performance and should not be used for that purpose.
Testosterone injection may also be used for purposes not listed in this medication guide.
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What Is Testosterone Cypionate
Testosterone cypionate is a prescription drug. It comes as an injectable solution given into the muscle. Testosterone cypionate is a self-injectable drug. You can give this medication to yourself at home after your doctor shows you how to do so.
Testosterone cypionate is available as the brand-name drug Depo-Testosterone. Its also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug.
Testosterone cypionate is a controlled substance. This means its regulated by the government.
Fat And Muscle Changes

Men generally have less body fat than women. This is partly related to testosterone, which regulates fat distribution and muscle maintenance in your body. With low T, youll likely notice an increase in body fat, especially around your midsection.
Your hormones also help regulate muscle growth. So, with low T, you may feel like youre losing muscle size or strength. However, this only occurs if your low T is prolonged and severe.
Testosterone shots can help regulate fat distribution, but you shouldnt expect significant weight changes from hormone therapy alone. As for muscle maintenance, testosterone therapy has been found to help increase muscle mass, but not strength.
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Study Finds Blood Clots Developed As Soon As 3 Weeks After Starting Therapy
A study first published on Aug. 7, 2013 in Clinical and Applied Thrombosis/Hemostasis found that blood clots developed as quickly as three weeks after men began using testosterone therapy drugs.
The study identified seven men who had used the drugs before or at the time they were admitted to the hospital for serious blood clots. The men experienced blood clots at 3 weeks, 1 month, 2 months, 3 months, 12 months or 27 months after starting TRT.
Our research found that 1.2 percent of men who landed in the hospital with dangerous and potentially lethal blood clots in the deep veins of the legs or in the lungs developed these clots within three months of starting testosterone therapy, study author Dr. Charles Glueck of the Jewish Hospital Cholesterol and Metabolism Center told the Cincinnati Business Courier.
According to Glueck, an inherited clotting disorder can increase the risk of blood clots. He said people should be tested for risk factors before beginning TRT.
Why Side Effects Occur With Low T Treatment
Some side effects seen with TRT are the direct result of the use of exogenous testosterone . Many occur only in the presence of higher testosterone levels, and still others are simply the consequences of the bodys normal metabolism of testosterone. This metabolism, or break down of testosterone, occurs in the same manner for both exogenous and endogenous testosterone , but because of an increased abundance of testosterone this may lead to higher than normal levels of these metabolites.
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What Other Information Should I Know
Keep all appointments with your doctor and the laboratory. Your doctor may order certain tests to check your body’s response to testosterone injection.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are receiving testosterone injection.
Do not let anyone else use your testosterone enanthate injection . Testosterone is a controlled substance. Prescriptions may be refilled only a limited number of times ask your pharmacist if you have any questions.
It is important for you to keep a written list of all of the prescription and nonprescription medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
What Are Side Effects Associated With Using Testosterone
Side effects of testosterone include:
- Excessive frequency and duration of erection
- Enlarged breasts in men
- High cholesterol
- High blood pressure
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Trt Side Effects: Prostate Changes
While prostate changes can occur with testosterone replacement, a study published in The Journal of Clinical Endocrinology & Metabolism in June of 2010, which looked closely at the adverse reactions reported in 51 other studies, found there to be no increased risk of the development of prostate cancer, prostate related urinary symptoms, or elevated PSA . That aside, because PSA is essentially a tumor marker for prostate cancer, patients with a first-degree relative who has been diagnosed with prostate cancer and those with an elevated PSA level should proceed with caution and be monitored closely.
For men with a personal history of prostate cancer, treatment for Low T is considered contraindicated according to most sources. It is important to note that testosterone replacement does not give you prostate cancer, but certainly elevated testosterone levels can cause an otherwise unnoticed prostate lesion grow more aggressively.
It is important to note that testosterone, in and of itself, is not a causative factor in the development of prostate cancer. That myth has finally been debunked through countless studies over several years while more recent data now indicate that a low serum testosterone levels are a potential predictor of high-risk prostate cancer. The more interesting debate at this point is the potential consequence of increasing a mans testosterone level, even to a normal range, in the presence of an existing prostatic growth.
How Long Does It Take For Testosterone Injections To Work
Testosterone injections can take a couple of months to begin fully working.
Depending on the dosage of testosterone injections you receive as well as how low your testosterone is when you begin injections will determine when you begin noticing a physical and mental difference.
If you want to learn more about how long testosterone treatment will take to work for you, give Port Orchard Natural Medicine a call to schedule a consultation with our naturopathic doctor to discuss your testosterone injection and testosterone therapy needs.
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We Rarely See These Side Effects And Have Ways To Address Them:
- Pain and redness at the injection site may also occur
If any of these effects occur please tell your doctor at Innovative Mens Clinic promptly.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is much greater than the risk of side effects and has created a plan to reduce any possible side effects and will help you address any side effects that may occur. Most people who use this medication do not see any negative side effects when it is used at normal doses, as prescribed by your doctor.
How Can I Avoid The Side Effects Of Trt

Negative side effects of testosterone replacement therapy can be reduced by consulting a qualified physician about your risk factors and submitting to routine blood testing before, during, and after therapy to detect any complications before they become unmanageable. Again, always seek expert medical attention.
Although TRT is generally safe for the majority of people, it does present a risk in select circumstances. By following your doctor’s recommendations, you can reduce your exposure to the potential side effects of TRT while increasing the benefits.
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Possible Side Effects Of Testosterone Therapy
WebMD lists a number of possible side effects from testosterone cypionate injections. The majority of these side effects are very rare when testosterone is used properly and estrogen levels are being addressed. In our effort to deliver the highest quality to you, we ask you to review the possible side effects and ask us any questions so we can ensure you understand how we are addressing these issues for you.
What Are The Good Side Effects Of Testosterone Replacement Therapy
The FDA has approved testosterone replacement therapy as a treatment method for men who lack or have low levels of testosterone in addition to an associated medical condition. If you have clinically low testosterone levels, using testosterone can improve your health, physical function, sexual performance, and overall well-being.
Potential benefits of TRT include:
- Improved sex drive: Because testosterone regulates your sex drive, it’s common to notice an increase in your level of interest in sex after starting TRT. You may notice that you are thinking about sex more frequently, getting aroused more easily, and having more sex with your partner.
- Improved sexual function and erections: With TRT, some aspects of sexual function may improve. Studies report that TRT may improve erections in men with mild erectile dysfunction.
- Better mood and increased quality of life: According to studies, TRT improves mood parameters such as energy levels and positive feelings in men with clinically low testosterone levels.
- Increased muscle mass and bone density: TRT may result in muscle growth and strength gain, as well as increase average bone mineral density.
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