Testosterone Replacement Therapy Dosage Considerations
If you are low in your free testosterone, your testosterone dose will reflect your free testosterone level. Equally important is watching your level of estrogen. Estrogen raises your sex hormone binding globulin. So you have to control your estrogen and you have to be looking at the free testosterone to know how much testosterone you should be taking.
On average the actual dose given per week is somewhere between 1 cc and 0.4 cc’s of testosterone 200mg/ml. There is a pretty big range of actual testosterone given between those parameters. At 0.4 cc you are getting 80mg and at 1 cc you are getting 200 mg. The 0.4 is a lower dose and 1 cc is a higher dose. I do have you know a few people that need 1 CC but it is few and far between. Just to give you an idea, maybe 10-15% of my patients on testosterone replacement therapy need this much. Most people are on the 0.5- 0.7ml range. Your dose can vary at any given time too based on how much you are exercising, how much stress is in your life, new medications, etc.
Now You Know More About The Ideal Testosterone Dosage For Strength Gains
Obviously, its advisable to talk to your TRT doctor and ask any questions you might have about testosterone dosage. Finding the ideal dose for you is also a matter of experimenting and seeing how you feel over time. Make sure that you keep a close eye on your blood work as well.
For more information about testosterone dosage for muscle gains, make sure that you check out this thread. Youll learn from other men who have different testosterone dosages and what was their experience while on TRT.
Testosterone Cypionate Quick Finder
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Misconceptions Surrounding Certain Compounds
Certain compounds that are very effective get completely overlooked because of their relative lack of potency, and oftentimes even their relative lack of side effects.
Wet compounds like Dbol will give the user an inflated look as a result of its conversion to 17-methylestradiol.
If something bloats you up 10 pounds nearly overnight, does that mean it is a more effective muscle builder than something dry but less dramatic due to its relative lack of side effects?
No, I don’t think so.
Compounds like Primobolan will get overlooked because of this, and they are seen as girl steroids.
If you’re in this for the long haul, long term muscle growth is our goal with the least impact on our health possible.
There are very few compounds that edge out Primobolan in this regard, despite yielding what may be perceived to be better increases in size in the short term.
The reality is, there are several commonly overlooked compounds with better outcomes than commonly reached for steroids not only in a clinical setting, but in a bodybuilding context as well in the long-term.
Comparing someone waterlogged on a Test, Nandrolone and Dbol cycle to someone on a Test, Primobolan and Nandrolone cycle, the guy on Dbol might appear to be making significantly more progress at a much faster rate, but are those outcomes just inflated by the guy being waterlogged?
Or are they actually yielding more nitrogen retention and lean muscle accrual with their inclusion of Dbol?
Dosage For Primary Hypogonadism
Adult dosage
- Typical starting dosage: Your dosage depends on your age and diagnosis. Your doctor will decide a dosage based on your needs. In general, the dosage is 50400 mg injected into your muscle every 24 weeks.
- Dosage increases: Your doctor may adjust your dosage based on your testosterone blood levels, response to treatment, and side effects.
- Maximum dosage: 400 mg injected into your muscle every 2 weeks.
Child dosage
- Typical starting dosage: Your childs dosage depends on their age and diagnosis. Your doctor will decide a dosage based on your childs needs. In general, the dosage is 50400 mg injected into your childs muscle every 24 weeks.
- Dosage increases: Your doctor may adjust your childs dosage based on their testosterone blood levels, response to treatment, and side effects.
- Maximum dosage: 400 mg injected into your childs muscle every 2 weeks.
Child dosage
It hasnt been confirmed that testosterone cypionate is safe and effective for use in children younger than 12 years.
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What Is The Ideal Testosterone Dosage For Muscle Gain
Theres no question that testosterone is paramount for achieving an increased muscle mass and reducing fat percentage. Both healthy young men and those reaching andropause can use exogenous testosterone to experience more gains in the gym or to achieve a particular body composition.
There are numerous ways testosterone can get into the body. Most people use injections, but you can also use creams, gels or pellets. However, whats the best and safest testosterone dosage for gaining muscle? This is what youre going to find out in this article, so keep reading.
What Should I Know About Storage And Disposal Of This Medication
Keep testosterone enanthate injection in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture . Do not refrigerate or freeze.
It is important to keep all medication out of sight and reach of children as many containers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location â one that is up and away and out of their sight and reach.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website for more information if you do not have access to a take-back program.
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How Is Testosterone Injection Given
Testosterone is injected into a muscle. The injection is usually given every 2 to 4 weeks.
Testosterone injections should be given only by a healthcare professional. Misuse can lead to serious side effects or death.
The length of treatment will depend on the condition being treated.
Testosterone will not enhance athletic performance and should not be used for that purpose.
While receiving this medicine, you will need frequent blood tests.
Testosterone can affect bone growth in boys who are treated for delayed puberty. Bone development may need to be checked with x-rays every 6 months during treatment.
When You Need Testosterone Treatmentand When You Dont
Most men have problems with erections from time to time. But some men have erectile dysfunction, or ED. This is when it is difficult to get or keep an erection thats firm enough for sexual intercourse.
If you have ED, you may think that testosterone treatment will help. Testosterone is a male sex hormone. After age 50, mens levels of testosterone slowly go down and ED becomes more common. But unless you have other symptoms of low testosterone, you should think twice about the treatment. Heres why:
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Warnings For Other Groups
For pregnant women: Testosterone cypionate is a category X pregnancy drug. Category X drugs should never be used during pregnancy.
This drug should only be used in males.
For seniors: This drug shouldnt be used to treat age-related decreases in testosterone. There isnt enough information from clinical trials in seniors ages 65 years and older to support the use of this drug for a long period of time.
If youre older than 65 years, you may be at a higher risk of heart disease, prostate cancer, and enlarged prostate while taking this drug.
For children: It hasnt been confirmed that testosterone cypionate is safe and effective for use in children younger than 12 years.
Testosterone cypionate may affect bone growth in children. This drug can cause bones to mature more quickly than normal without causing an increase in height. This can result in a shorter adult height. Your doctor will check your childs growth regularly if your child takes this drug.
All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:
- how severe your condition is
- other medical conditions you have
- how you react to the first dose
What Other Drugs Will Affect Testosterone
Certain drugs may interact with testosterone, including
- Blood thinners
- Anti-inflammatory drugs, such as oxyphenbutazone
Other prescription and over-the-counter medicines, vitamins, and herbal products may also react with testosterone. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
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Why Is This Medication Prescribed
Testosterone cypionate , testosterone enanthate , testosterone undecanoate , and testosterone pellet are forms of testosterone injection used to treat symptoms of low testosterone in men who have hypogonadism . Testosterone is used only for men with low testosterone levels caused by certain medical conditions, including disorders of the testicles, pituitary gland , or hypothalamus that cause hypogonadism. Your doctor will order certain lab tests to check your testosterone levels to see if they are low before you begin to use testosterone injection. Testosterone enanthate and testosterone pellet are also used to stimulate puberty in males with delayed puberty. Testosterone enanthate injection may be used in certain women with a type of breast cancer called mammary cancer that has spread to other parts of the body. Testosterone should not be used to treat the symptoms of low testosterone in men who have low testosterone due to aging . Testosterone is in a class of medications called androgenic hormones. Testosterone is a hormone produced by the body that contributes to the growth, development, and functioning of the male sexual organs and typical male characteristics. Testosterone injection works by supplying synthetic testosterone to replace the testosterone that is normally produced naturally in the body. When used to treat breast cancer, testosterone works by stopping the release of estrogen.
What Are Warnings And Precautions For Testosterone
Warnings
Serious pulmonary oil microembolism reactions, involving urge to cough, dyspnea, throat tightening, chest pain, dizziness, and syncope reactions and episodes of anaphylaxis reported during or immediately after administration of testosterone undecanoate injection may occur after the first dose
Observe patients for 30 minutes in a healthcare setting to provide immediate medical treatment in event of serious POME reactions or anaphylaxis
Because of the risks of serious POME reactions and anaphylaxis, testosterone undecanoate is available through a restricted program under evaluation and mitigation strategy called the Aveed REMS Program
This medication contains testosterone. Do not take Aveed, Depo-Testosterone, Delatestryl, or Testopel if you are allergic to testosterone or any ingredients.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
Contraindications
- Hypersensitivity to this hormone or formulation components
- Cancer of breast or known or suspected carcinoma of the prostate in men
- Severe cardiac, hepatic, or renal disease
- Women: Pregnancy or prospect of pregnancy
Effects of Drug Abuse
Short-Term Effects
Gynecomastia.
Cardiovascular Risks
Edema
Healthy males with delayed puberty
- Monitor bone maturation by assessing bone age of wrist and hand every 6 months
- May accelerate bone maturation, compromising final adult height
Pregnancy and Lactation
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Beneficial Effects Of Testosterone On The Heart
The lower rate of heart disease in women has historically been attributed to the cardioprotective effects of estrogen. Presently, this position is being reexamined. The cardioprotective effects of estrogen have come into some question and there is emerging evidence that testosterone may have cardioprotective effects of its own. Swartz and Young have shown that older men with a low circulating testosterone, a higher fraction have previously suffered a myocardial infarction. Testosterone supplementation in hypogonadal men improves exercise tolerance and decreases exercise-associated ischemia in elderly patients with coronary artery disease and low or low-normal testosterone. This protection may be secondary to a vasodilatory effect and/or higher pain threshold. The vasodilatory effect has been confirmed in animal models . The beneficial effects are seen with both acute and chronic testosterone administration, and also with low and high dose supplementation. However, none of these studies was long enough to show an effect on cardiovascular mortality.
Different Protocols Have Different Looking Outcomes
Indeed, different protocols WILL have very different outcomes. We can immediately visualise this with predictive graphs derived from pharmacokinetic models. As a little preface, these graphs are computationally made by The Mens Health Clinic, created using Python 3.8, some modules, some pharmacokinetics and a lot of maths. The real outcomes from different protocols can vary greatly based on individual multifactorial differences, and we can only account for so much. However, these predictive model graphs serve as good starting points, and give us a very good insight into how different protocols may on average look in real life.
We have broken this down into the different protocols by sector, including the NHS. So, without further ado, let us start with the NHS.
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Introduction To Testosterone Replacement Therapy
Testosterone replacement therapy is a treatment in which additional testosterone is added to a mans body , to increase the concentration of testosterone in his body. It is used to treat hypogonadism, a condition characterised by low levels of testosterone in the blood and clinical symptoms of testosterone deficiency . Hypogonadism occurs when a mans testes do not produce enough testosterone, either because the testes are not working properly, or because the hypothalamus or pituitary gland in the brain are not working properly. The hypothalamus and pituitary glands produce hormones that stimulate testosterone production in the testes.
The aim of testosterone replacement therapy is to increase blood testosterone concentrations to normal levels. In doing so, it can also restore the mans sex drive and expression of male sex characteristics .
Testosterone is one of the oldest marketed drugs and has been used in testosterone replacement therapy since the 1930s.
Before Taking This Medicine
You should not receive testosterone if you are allergic to it, or if you have:
-
prostate cancer
-
if you are bedridden or otherwise debilitated or
-
if you take a blood thinner .
This medicine can harm an unborn baby. Do not use testosterone if you are pregnant or may become pregnant. Tell your doctor right away if you become pregnant during treatment. Use effective birth control while you are receiving this medicine.
It is not known whether testosterone passes into breast milk or if it could harm a nursing baby. You should not breastfeed while using this medicine.
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Beneficial Effects Of Testosterone On Muscle And Bone
Testosterone produces substantial anabolic effects in young and middle-aged hypogonadal men . In contrast, the anabolic effects of testosterone replacement therapy in older men have been harder to demonstrate. Among the many published trials of testosterone in older men, some report strength gains and some do not. Only a few report strength gains that can be considered substantial in comparison to the benefits of resistance exercise training. In most cases, the studies reporting significant strength gains were performed in hypogonadal subjects and employed a higher dose of testosterone, for a longer duration.
The dose of testosterone also appears to be critical in determining whether increases in bone mineral density are observed. Snyder et al treated older hypogonadal and eugonadal men for 36 months with 6 mg testosterone/day by patch and found that bone mineral density did not increase overall, but did do so in the group with the lowest pretreatment testosterone levels. However, Amory et al treated older hypogonadal men for 36 months with biweekly i.m. injections of 200 mg testosterone enanthate and obtained substantial increases in bone mineral density, 3%4% in the hip and a remarkable 10% in the lumbar spine.
Male Breast Cancer Risk
A 2006 study suggested an 11 percent increase in male breast cancer risk over a 10-year period of TRT use. The mechanism for this link is poorly understood and it hasn’t been verified.
For cis men with untreated breast cancer, the FDA remains firm that use of testosterone poses a potential threat and should be avoided without exception. This is because of the conversion of testosterone into estradiol that happens naturally.
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More Information Regarding Types Of Testosterone
Our medical team at the biostation can help you determine which of the four different types of injectable testosterone therapy is best for your health goals and lifestyle. the biostation even offers custom blends for maximum results. In some cases, utilizing multiple esters improves the bodys response, further enhancing outcomes.
How Does This Medication Work What Will It Do For Me
Testosterone belongs to the class of medications called androgens . This medication is used to replace testosterone in men who have conditions caused by low testosterone levels, such as erectile dysfunction . There are other possible causes for erectile dysfunction, so testosterone is only used to treat erectile dysfunction that is caused by low testosterone.
This medication works by replacing the testosterone that the body is missing. Testosterone cypionate should only be used if testosterone deficiency has been confirmed by symptoms and blood tests.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
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