Work With Not Against Melatonins Sleep
Melatonin levels rise about two hours before bedtime, Buenaver says. Create optimal conditions for it to do its job by keeping the lights low before bed. Stop using your computer, smartphone or tabletthe blue and green light from these devices can neutralize melatonins effects. If you watch television, be sure youre at least six feet away from the screen. Turn off bright overhead lights too. Meanwhile you can help program your body to produce melatonin for sleep at the right time of day by getting exposure to daylight during the morning and afternoon. Take a walk outside or sit beside a sunny window.
How Much Do I Take
The ideal dose of melatonin has not been standardized because it varies upon age and purpose.
For young adults, a dose of 0.1-0.3mg before sleep is adequate because it will raise nighttime plasma concentrations into the normal range. In my practice we stay low, at physiologic dosing, 0.5 1.5 mg. There are times when more is warranted, but remember, it should be used to establish bedtime habits, not as a sleeping pill.
How To Take Melatonin
You donât need a big amount of melatonin to see any benefit. Taking more of it doesnât make it work better or faster. Start with a small dose. If you find you need more, you can slowly take more over time.
When you take it may be even more important than how much you take. The best timing of your dose depends on the sleep issue youâre trying to solve:
- To deal with jet lag, take it when you arrive at your destination at the time youâd like to go to bed. Some studies have found that taking it as early as 3 days before your trip can help jet lag symptoms. Keep in mind, though, that melatonin is best when youâre traveling east. Thereâs no evidence that it helps you adjust to westward travel.
- If you work the night shift, take it at the end of your workday, but never before you drive home.
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Dangerous Interactions Could Occur
The supplement could also interfere with other important medications, including blood thinners, diabetes drugs, immune system-suppressing drugs, anti-seizure drugs and some contraceptives. If youre taking any type of medication, its important to talk to your HCP before taking melatonin or any other dietary supplements.
What Melatonin Is Used For

“The most popular use of melatonin is for people who have trouble falling asleep,” says Alex Dimitriu, M.D., who is double board-certified in psychiatry and sleep medicine and is the founder of Menlo Park Psychiatry & Sleep Medicine in Menlo Park, California.
“Melatonin is also referred to as the ‘hormone of darkness,’ because it’s produced by the pineal gland in response to low light, like the evening sunset. It works to help us prepare for sleep and enter those deep sleep stages,” he says.
Those with a healthy circadian rhythm should naturally secrete enough melatonin to send the signal for bedtime. However, factors like stress1 from screens, and caffeine3 can all inhibit its production. Taking melatonin in supplement form is one way people try to get levels of the hormone back on track, but this is also tricky .
Melatonin has other nighttime perks, too, adds Jacob Teitelbaum, M.D., a board-certified internist in integrative medicine and sleep expert. “Research has shown that melatonin is a potent antioxidant,” Teitelbaum explains, and it can promote digestive health to help people sleep better and more comfortably.
. Those who are older and take melatonin to balance their circadian rhythm may have more success with it5, one 2005 study published in the Journal of General Internal Medicine found.
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Wondering Why Melatonin Doesnt Work For You Heres What The Science Says
So, youve tried some melatonin supplements to help you fall asleep, but you haven’t gotten a good night’s sleep with them. Now youre wondering, Why does melatonin not work for me? Thankfully, theres a lot more you can do to get the most out of your melatonin such as trying more effective melatonin supplements or improving your nighttime routine.
In reality, it is possible that melatonin supplements dont work for some people. We estimate that this may be true of about 3-5% of the population. However, if youre not feeling the effects of melatonin, its much more likely youre taking it at the wrong time, youre not taking the right amount, or your habits are working against the melatonin. Read on to learn all the different things you can try before concluding, Melatonin doesnt work on me.
Note: If melatonin alone doesnt work for you, try MELO Sip. MELO Sip combines melatonin with other ingredients like L-Theanine, Valerian root, and Chamomile that help you relax when melatonin alone isnt enough.
In this post, we’ll cover:
Is It Safe To Take Melatonin Every Night
Unfortunately, theres no straight answer here, which youre probably hoping for. There isnt any evidence proving conclusively that long-term use of melatonin is safe. Though the supplement is generally not associated with dependency, habituation, or hangover symptoms, Dr. Kohli says she doesnt suggest taking melatonin every night because of the lack of long-term clinical trials evaluating the safety of chronic use.
At the same time, there isnt any evidence proving nightly melatonin use isnt safe. Dr. Bollu points out that melatonin is a natural hormone that fluctuates in our bodies on a daily basis anyway, meaning it may be safer than taking a prescription drug.
RELATED: Is it safe to take OTC sleep aids every night?
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Why Melatonin Is Bad For You
If its all natural, why is melatonin bad for you? my mom asked, when I expressed my concern with this supplement after learning that she takes it on-and-off for her insomnia. Boy, have I got a blog post for you! I replied.
In short, melatonin is a hormone that correlates with sleep cycles and plays beneficial roles in numerous physiological functions. But melatonin supplements are neither a safe, natural nor effective solution to insomnia.
Try A Different Type Of Melatonin Supplement
As we saw earlier, most melatonin supplements have poor bioavailability. This is in large part because most melatonin supplements are pills. Pills take time and energy to be broken down by your body, and a substantial amount of the supplement they contain wont get absorbed by your body.
Consider trying a melatonin liquid or vaporizer. Both are known to have much better absorption rates than melatonin pills. Youll absorb them more quickly, and youll also absorb more of whats in them, meaning youll need a lower dose of these products than youd need if you were taking a pill.
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Melatonin For Sleep: Does It Work
Melatonin sleep aids are growing in popularity, with 3 million Americansusing them in 2012, according to a nationwide survey from the Centers forDisease Control and Prevention. If youre among them or are consideringmelatonin for sleep, its smart to understand exactly how melatonin works.
Your body produces melatonin naturally. It doesnt make you sleep, but as melatonin levels rise in the evening it puts you into a state of quiet wakefulness that helps promote sleep, explains Johns Hopkins sleep expert Luis F. Buenaver, Ph.D., C.B.S.M.
Most peoples bodies produce enough melatonin for sleep on their own. However, there are steps you can take to make the most of your natural melatonin production, or you can try a supplement on a short-term basis if youre experiencing insomnia, want to overcome jet lag, or are a night owl who needs to get to bed earlier and wake up earlier, such as for work or school.
If youd like to harness melatonins sleep-inducing effects, Buenaver recommends taking these steps.
Your Supplement Doesnt Actually Have The Advertised Amount
Lets say youve been responsible with your melatonin dosage, starting with a small amount and slowly working your way towards slightly higher doses. You might still be taking the wrong amount, for reasons that arent your fault.
This is because the contents of many melatonin supplements dont actually match the amounts advertised on their labels. In fact, a study from the Journal of Clinical Sleep Medicine found that 71% of melatonin supplements deviated from the amount on their labels by more than 10%. Thats a vast majority of melatonin supplements that have a significantly different amount of melatonin than what theyre telling you.
The problem goes in both directions, too: Some melatonin supplements have less than what they advertise, and some have substantially more. Worse still, the Journal of Clinical Sleep Medicine Study also found that 26% of melatonin supplements contain serotonin. Serotonin is a hormone produced by the pineal gland known to promote wakefulness .
All products from MELO Labs have a Certificate of Analysis verifying the accuracy of the product labels. Were also in the process of having our products third-party tested, so you dont have to take our word for it.
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Day : I Was Feeling Positive About Melatonins Effects
On day two, I had a pretty busy day scheduled. I woke up feeling like I had an amazing nights sleep. Although I did feel a bit of sleepiness in the morning, I couldnt tell if that was the melatonin or the fact that Id slept so well I just didnt want to get out of bed.
That evening, I took melatonin about a half hour before bedtime and fell asleep quickly and easily.
Melatonin Is A Key Recommendation In Covid

There are a number of important nutritional considerations in both the prevention and treatment of COVID-19. There is one that really stands out to me that has not received the same sort of promotion as others like vitamin D and zinc. The title of this newsletter gives it away. I am referring to melatonin as a critical supplement in the battle against this virus. It makes sense, melatonin exerts significant immune enhancing effects and patients at highest risk, e.g., the elderly and those with high blood pressure, type 2 diabetes, and various other chronic diseases are all associated with melatonin deficiency. Preliminary evidence discussed in this newsletter will highlight the use of melatonin as safe and potentially valuable in the prevention and treatment of COVID-19.
Background Data:
Melatonin is a compound that is produced by the brains pineal gland that is well-known as a natural sleep aid. Sleep is obviously critical to proper immune function, but melatonins immune enhancing effects go well beyond helping people sleep better. Melatonin is very important in protecting the cells that line the respiratory and gastrointestinal tract from infection and damage. In fact, these cells produce more than 400 times the amount of melatonin each day as the brain does. Melatonin does not directly kill viruses, but it does have indirect anti-viral actions via its effects on the immune system. It also works closely with vitamin D3 in regulating the immune response.
New Data:
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Try Taking A Break Or Cutting Back If Youve Been Taking Too Much
If youve regularly been taking higher doses of melatonin, say 10 mg, and youre not finding this effective, its best to stop at this point rather than continuing to increase the dose. Give your body a chance to reset its natural circadian rhythm and sleep cycle before trying again.
After taking a break from melatonin supplements, at least a few days but maybe up to a week, try starting at a much lower dose. A case report from the Journal of Intellectual Disability Research found that taking a break and then resuming with a much lower dose could help make melatonin more effective in those whove developed a high tolerance.
Why Melatonin Doesnt Work For You
Many of the reasons melatonin doesnt work are related to specific supplements. It can be difficult to find a good melatonin supplement, not least because these supplements arent regulated by the FDA. This is why we started MELO Labs: to create more effective, fast-acting, and transparent melatonin supplements.
With this in mind, lets talk about some of the reasons why melatonin might not be working for you.
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Melatonin Doesnt Work For You
If youve carefully experimented with all of the above strategies and still find melatonin supplements to be ineffective, it is possible melatonin doesnt work for you. That said, you still might not want to give up on melatonin completely.
For instance, if you regularly have trouble falling asleep due to anxiety, melatonin wont counter your anxiety. However, some melatonin supplements contain additional compounds known to help with reducing anxiety and increasing relaxation. Both MELO Air and MELO Sip contain L-Theanine, and MELO Sip also contains valerian root extract, chamomile extract, GABA, potassium, zinc, and a variety of other nutrients all known to support sleep.
If your problems with sleep are rooted in anxiety, consider a melatonin supplement with additional relaxation-enhancing compounds, such as MELO Sip.
Learn more about MELO Labs fast acting melatonin supplements: MELO Air and MELO Sip.
How To Choose A Melatonin Supplement
Theres a lot to be desired when it comes to supplement reliability, suggests research in Clinical Sleep Medicine. For instance, it found melatonin content in supplements ranged from 83% less to 478% more than the concentration declared on the product label. It also found shocking lot-to-lot variabilitymelatonin levels varied by as much as 465% when comparing different batches of the same product from the same manufacturer.
Grandner says there isnt much a consumer can do except buy from a brand with a good reputation. Look for the bigger and more established companies, he says. They have more to lose if they sell inferior products.
Don’t Give Up On Your Dreams So Soon – Discover Prima Sleep Tight
Prima’s Sleep Tight softgels are a melatonin-free doctor formulated blend of CBD, amino acid compounds 5-HTP and GABA, and calming herbs.
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Try A Natural Solution
One way to help your body sleep is by adjusting your diet. Many people have found that using hemp flower in their diet helps their body relax and sleep better. According to Sweet Leaf Hemp Farms, not all strains actually help you sleep, so you should research and experiment before committing to hemp flower. You might be concerned about addiction. This is a common misconception with hemp flower. Hemp flower is related to marijuana but doesnt contain high enough levels of THC to give you a high or be addictive. In fact, hemp flower is an extremely safe thing to use.
Can You Overdose On Melatonin
Its unlikely that youll suffer any serious side effects if you take a large dose of melatonin, but you may not feel so great, either, says Grandner. You could experience nausea or a headache. However, it wont last longmelatonin only stays in the body for about five hours.
A Bedtime Routine Like No Other
Struggling with low-quality sleep and need a bit of extra support to regulate your natural sleep cycle? Discover Prima Sleep Tight softgels.
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More Reasons That Less Is More
Melatonin can affect fertility! In women, it can change progesterone, estradiol, luteinizing hormone and thyroid levels. In men, regular use of the darkness hormone can lower libido and can affect sperm both decrease the count and slow it down. Remember, high levels of melatonin can suppress puberty in children. Additionally, too much melatonin taken at once can cause headaches, dizziness, nausea, or irritability. Very high levels of melatonin are associated with daytime grogginess, tiredness, and hypothermia.
Melatonin Can Make You Groggy: 3 Alternative Sleep Supplements To Try Instead

These supplements can help you get a good night’s sleep without facing a “melatonin hangover” the next morning.
Mercey Livingston
CNET Contributor
Mercey Livingston is a health and wellness writer and certified Integrative Nutrition Health Coach. She’s written about fitness and wellness for Well+Good, Women’s Health, Business Insider, and Prevention.com among others. When not writing, she enjoys reading and trying out workout classes all over New York City.
Melatonin is one of the most popular over-the-counter supplements for people who have trouble sleeping — and like so many others, I’ve tried it out in an effort to get better rest at night.
However, the few times I’ve taken any amount of the supplement, I’ve felt groggy and “hungover” for hours the next morning. My body’s negative reaction to melatonin seems to defeat the purpose of taking it in the first place: to feel more rested during the day. So, I decided melatonin’s not the best sleep aid for me.
Turns out, I’m not alone.
Below, Josh Axe, a clinical nutritionist and co-founder of Ancient Nutrition, shares the best alternatives to melatonin if you decide it’s not for you. Plus, he breaks down why melatonin can make you feel hungover — and how to prevent that effect if you choose to keep taking it.
Melatonin takes about an hour to work and lasts for about five hours, according to Josh Axe.
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How Much Melatonin Should I Take
Melatonin supplements are available in a wide range of dosages, from 1 milligram up to 10 milligrams, and can be taken in pill form, as dissolvable tablets, liquid drops, or even gummies. However you take it, the best time to use melatonin is about 30 minutes before bedtime.
If youve never taken melatonin before, start small and work your way up if needed. For adults, Dr. Kohli recommends beginning with a 1 to 2 milligram dose daily and increasing the dosage by another 1 to 2 milligrams at a time. For children, the AAP says the dose should remain low , capping out at no more than 3 to 6 milligrams of melatonin. The maximum dosage for healthy adults ranges from 5 to 10 milligrams. If that sounds like a wide spectrum of normal, its because the right dose of melatonin is very individualized. According to University of Missouri Health Care neurologist Pradeep Bollu, MD, while some people respond well to 3 milligrams daily, others may need more or less. If you feel like you need more than 5 milligrams, you should talk to your doctor first before trying a higher dose. The more melatonin you take the more likely you are to have side effects. Melatonin dosage is fixed according to age, and does not vary by body weight.